Restylane® Injections in Chicago, IL

Restylane Family of Dermal Fillers

Restylane® was the original dermal filler, first approved by the FDA for use in the United States in 2006. Since that debut, Restylane® injections have become one of the world’s most popular aesthetic treatments.

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Over the years, Galderma, the manufacturer of Restylane®, has added new fillers to extend the Restylane® line. Each filler targets a different area of the face. Dr. Wiener offers virtually the entire Restylane line: Restylane®, Lyft, Refyne, Defyne, and Kysse.

What is Restylane® ?

The Restylane® family is a line of dermal fillers. Dermal fillers are broken into either “natural” or “synthetic” distinctions. All Restylane® fillers are natural fillers because they are made primarily from hyaluronic acid, a naturally occurring substance in the human body whose job is to hydrate, plump, and firm the skin. When these fillers are injected beneath a crease, such as a nasolabial fold, the hyaluronic acid binds with nearby water molecules, adding volume and plumping the skin. This erases or substantially decreases the wrinkle or it returns volume to an area such as the lips or the backs of the hands.

Who is a good candidate for the various Restylane® fillers?

The question of whether you’re a candidate for a dermal filler, such as Restylane® or Juvederm®, or a neuromodulator, such as Botox®, is the kind of wrinkles you want to target. If your wrinkles and lines occur on the upper third of your face, they are likely due to muscle contractions under the skin when you make expressions such as frowning, showing surprise, or squinting. These are known as dynamic wrinkles. Over time, repeated muscle contractions begin to form wrinkles on the skin above them. These are crow’s feet, the 11s between your eyebrows, and forehead lines. Dermal fillers have no effect on dynamic wrinkles. This is the domain of Botox®.

However, if your wrinkles and creases are on display at all times — things like laugh lines, barcode lines around your lips, parentheses lines, and areas of volume loss such as the cheeks — then Restylane® and other dermal fillers are the answer. This type of wrinkle is known as a static wrinkle. Static wrinkles are the result of sun damage, declining collagen production, environmental factors, and personal habits such as smoking. Botox® has no effect on static wrinkles; they are conquered by dermal fillers.

What are the various Restylane® fillers and where are they used?

Originally, Restylane® was a single filler. Over the years, an entire family of Restylane® fillers has been developed, each targeting a specific area of the face. Dr. Wiener has researched each new addition in the line, and he now offers the entire line except Silk. In place of Silk, he prefers the newer Restylane® Kysse. Each filler is intended for a different area of the face. Here are the descriptions of each Restylane® filler, what types of wrinkles they target, and how long you can expect them to last.


This was the flagship product, the first dermal filler. It remains very popular around the world. It targets marionette lines, nasolabial folds, and other wrinkles by adding volume beneath the wrinkle or crease and pushing the surface skin upward. Its results last from 6-9 months.

Restylane® Kysse

Restylane® Kysse is specifically meant for use on the lips. Once injected, Kysse adds fullness to the lips, and it helps smooth wrinkles on and above the upper lip (perioral lines). Kysse is different from Silk because it is the first dermal filler to be equipped with Optimal Balance Technology, also known as XpresHAn Technology. This technology enables Kysse to integrate into the tissues in the injected areas to achieve a more natural look. Galderma says this technology looks and feels more natural with the many movements of our lips. Kysse also delivers longer results than Silk, lasting up to one year.

Restylane® Lyft

Restylane® Lyft adds volume to the cheeks and corrects smile lines. Lyft also can be used to replace volume loss on the hands. Results last from one year to 18 months.

Restylane® Refyne

Restylane® Refyne was approved by the FDA in December 2016. This addition to the Restylane® line (along with Defyne, see below) is used to correct smile (marionette) lines and nasolabial folds. Refyne is specifically formulated to treat mild to moderate lines and wrinkles. Galderma has cross-linked the gel in Restylane® Refyne and Defyne to help support the patient’s natural expressions — for real-life results that help maintain natural movement when smiling, frowning, or otherwise moving your mouth.

Restylane® Defyne

Approved along with Refyne, Defyne also specifically targets nasolabial folds and marionette lines. The difference is that Defyne is designed for use on moderate to severe creases and lines. Both Refyne and Defyne provide results that last up to one year.

What are the side effects with Restylane® fillers?

Because all Restylane® fillers are made primarily with hyaluronic acid (which occurs naturally in the human body), allergic reactions are almost unheard of. The common side effects with all dermal fillers are swelling, redness, pain, bruising, tenderness, and itching at the injection sites after your session. Some patients have been known to develop headaches for the first day or two, but this is rare. These side effects are typically mild but may last for up to a week when treating smile and marionette lines. On the lips, they may last 10-14 days.

Occasionally, lumps will form at the injection sites. This is rare, but if it happens, they can be quickly resolved by an injection of hyaluronidase. This is an enzyme that instantly degrades the hyaluronic acid, eliminating the lump.

What’s most important with the use of dermal fillers or Botox® is the experience of the injector. Dr. Wiener is a board-certified plastic surgeon, and he has extensive training from Galderma and Allergan with all of the injectables he provides for our patients from all across the Chicagoland area, so you can be sure you’ll get the results you’re seeking.

There isn’t any downtime with any Restylane® filler.

Do I need multiple treatments with Restylane® ?

All Restylane® fillers (as well as the other dermal fillers and Botox® Dr. Wiener offers) are delivered in a single treatment. Dr. Wiener injects the various filler options into the areas you seek to treat. This only takes a few minutes. From there, your results last for various durations, as described above. When the fillers eventually break down and are absorbed, you will need another session to maintain your results, but that won’t be for at least 6 months, all the way up to 18 months.

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For more information on Restylane® or to schedule your appointment, call us today at 773.763.3990!

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